Home » Products » Liquid Preparation & Filling Machine » Aseptic Blow-Fill-Seal System » Blow fill seal machine pharmaceutical pp bottle iv solution production line

Blow fill seal machine pharmaceutical pp bottle iv solution production line

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  • 1150pcs/h

  • New

  • Automatic

  • Electric

  • 380V/220V 50Hz

  • Liaoning, China

  • 2021

  • Xianglong

  • 4000*4000*6000mm

  • 12000

  • 2 years

  • High-accuracy

  • Ordinary Product

  • Provided

  • Provided

  • 2 years

  • PLC, Motor

  • pharmaceutical factory

  • Japan, Germany, United Kingdom, Ukraine, Mexico, Spain, Pakistan

  • Filling Machine, AFP Blow-Fill-Seal Plastic (SVP)

  • Plastic

  • 20-1000ml

  • Aseptic packing

  • PP/PE

  • 9600 / 6000

  • Food, Beverage, MEDICAL, Chemical, Pharmaceutical

  • Bottles

  • Beer, Milk, Water, Oil, Juice, Pharmaceuticals

  • GMP ; IOS

Product Description

Aseptic Blow-Fill-Seal System

BFS is short for Blow-Fill-Seal technique. It has been developed so that formation for the container, filling and sealing takes place in a single machine under a controlled environment that enables the packaging of a pharmaceutical liquid in an aseptic manner. As the container is made, filled and sealed within a single machine and protected by sterile laminar air, the chance of contamination is very remote. Moreover, during the whole cycle, all process media like solution, air & etc. are previously sterile filtered and open containers remain exposed to the clean room air for less than 1.5 seconds. The Blow-Fill-Seal technology become the process of choice when contamination of particle and microbial are primary concerns in a production.

Blow-Fill-Seal Technique

The Blow Fill Seal Technique has been developed so that formation of the container, filling and sealing takes place in a single machine under a controlled environment that enables the packaging of a pharmaceutical liquid in an aseptic manner. The following picture show the major phases in the integrated packaging of parenteral solutions using the AFP® system. Aseptic packaging process As the container is made, filled and sealed within a single machine and the process is protected using a sterile air shower and additionally, all process media (solution, air etc.) are sterile filtered, the chance of contamination is very remote. Adding to the fact that during the whole cycle, open containers remain exposed to the clean room air for less than 1.5 seconds, the Blow-Fill-Seal technology becomes the process of choice where contamination of
particle matter and microbial contamination is a primary concern.
Extrusion
With high speed screw rod, thermoplastic material is continuously extruded in a tubular shape. Aseptic air blows to the plastic
tube parison, and the parison goes through the forming mould.
Blowing
The main forming mould closes and the bottom of plastic parison is sealed. The cutting knife cut the parison.The top of plastic
parison is located by the open protecting clamp.Aseptic air continuously protects the open tube parison.The plastic material is
formed into containers as determined by the design of the mould by vacuum and/or aseptic compressed air.
Filling
The containers are filled immediately and the air in the container is displaced .In the filling process,the containers are protected by the aseptic air as Grade A.
Sealing
At the same time,the tube parison between top of plastic mould and the open protecting clamp remains semi-melting condition,and
then the sealed mould closes and forms the top of the container and keeps the container sealed.
Outfeeding
After sealed, the mould is opened, and the containers are totally formed, filled, sealed and is ready to outfeed. Then the machine
starts the next cycle.
Details Images
Specification
Model
Specification
No.of Extruding Heads
Distribution of Cavity
Total Cavities
Capacity(pcs/h)

AFPL6
500ml
6
6
6
1150
1000ml
6
6
6
1080


AFPL8
100ml
8
8
8
1950
250ml
8
8
8
1800
500ml
8
8
8
1550

AFPL6D
500ml
6
2*6
12
2350
1000ml
6
2*6
12
2460


AFPL8D
100ml
8
2*8
16
4000
250ml
8
2*8
16
3600
500ml
8
2*8
16
3100
Note:The products of our company may always be updated, and are subject to change without (the real products shall prevail).
Product Application
This product biological preparation hyaluronic acid human and animal vaccine eye drops for injection drug sterile preparation and other fields are applicable.
Old style optical, aural, nasal care products need adding preservative in order to assure a controllable shelf life after opening.
Whereas no preservatives needed for the dispos-able&quantitative ampoules produced by BFS machine, therefore there is no allergy
risk for patients.
Related products
Packing & Delivery
Company Profile
Liaoyang Xianglong Internaitional Machinery Trading Co., Ltd. is originated from Liaoyang Pharmaceutical Machinery Plant (which was the first state-owned pharmaceutical machinery plant in China and was founded in 1947), and is professional in the manufacturing & trading of variable kinds of pharmaceutical devices, including separating machines, drying machines, liquid /powder /capsule/ pills filling machine, cartonning machines, membrane packing machines and glass-lined tanks, etc. With professional technicians and strict quality control system, our machines are widely applied in industries of pharmaceutical, petrol, chemical, food and environment protecting, etc., and besides our regular customers in China, our machines have been exported to many countries & regions in Europe, America, Southeast Asia, Africa, South America and the Middle East, etc., and good reputation is gained.
FAQ
Q1: Are you a manufacturer or a trader?
A: As a professional manufacturer, we have our own factory, and if a customer has reasonable demand, out machine can be customized.

Q2: How do you ensure the machine quality?
A: As a professional manufacturer of pharmaceutical devices for more than 15years, with strict management, advanced
processing technologies and professional workers, we are confident for our machines quality. And before any
machine is delivered, will be carefully tested.

Q3: How can I trust you for the first cooperation?
A: Since our company was founded, we have registered in China Industry and Commerce Bureau. We passed the SGS &
ISO certification, and we are a senior member in Alibaba international platform (more than 12years). For the first deal between us, the Alibaba's Trade Assurance service can be used, which will fairly protect your rights and money throughout the transaction process.

Q4: How do I place an order, and how is it completed?
A: Under the condition that the buyer is satisfied with the quotation and pre-sales service:
1. Both of parties sign on a contract, and then the seller prepare the PI.
2. The buyer arranges the down payment.
3. The seller prepares the machines.
4. After the machine is completed, have the test & trial run.
5. Before the delivery, if the buyer requires, have the necessary inspecting.
6. As per the contract/ PI amount, the buyer balances the payment.
7. The machine is going to be shipped.
8. After the machine is received, the seller provide the buyer guidance for the installation and the debugging.
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